胎儿暴露在一个高糖环境下可导致其成年后发生高血压和肾功能不全。研究人员评估肾交感神经在糖尿病大鼠后代高血压和肾脏疾病中所起的作用。方法:在交配前诱发雌性Wistar大鼠发生糖尿病(链脲霉素60mg/kg,腹腔注射)。对对照组(n=18)和糖尿病组(n=19)雌性大鼠3月大的雄性后代进行研究。 Exposure of the fetus to a high-sugar environment can lead to hypertension and renal insufficiency in adulthood. The researchers evaluated the role of the renal sympathetic nerve in the development of hypertension and kidney disease in the offspring of diabetic rats. Methods: Female Wistar rats were induced to develop diabetes (streptozotocin 60 mg / kg, ip) before mating. Male, 3-month-old male offspring of control (n = 18) and diabetic (n = 19) females were studied.