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目的:通过与二维超声的对比研究四维超声在胎儿产前唇腭裂畸形中的诊断价值.方法:通过将我院进行产前检查的孕妇随机分为试验组和对照组,分别使用腹部凸阵探头和容积探头进行检查.记录胎儿唇腭裂畸形的诊断率、漏诊率、疑诊率,应用x2检验对数据进行统计学分析.结果:共检出胎儿唇腭裂畸形89例,其中实验组58例,确诊率为87.9%,漏诊率为1.5%,对照组31例,确诊率为68.9%,漏诊率为15.5%.确诊率比较差异有统计学意义(P<0.05).四维超声在诊断单纯行唇腭裂与非单纯唇腭裂均优于二维超声组,差异有统计学意义(P<0.05).结论:四维超声在诊断胎儿产前唇腭裂的确诊率方面优于二维超声,是一种值得推广的检查方法.“,”Objective To explore the application value of four-dimensional ultrasonography in the diagnosis of prenatal cleft lip and palate. Methodswomen that prepare for give birth to a child were randomized into two groups, experiment group and control group, all of them adopt color doppler ultrasound GE voluson s6 to physical examine. The aberration rate, misdiagnosed rate, suspected rate were recorded, x2test was used for statistical analysis.ResultsA total of 89 patients were identified, there are 58 patients in the experimental group and 31 patients in the control group, the accurate diagnosis rate is 87.9% and 68.9% in the experimental group and control group respectively, and the difference is statistically significant(P<0.05), rate of missed diagnosis in the experimental group and control group is 1.5% and 15.5% respectively, and the difference is statistically significant(P<0.05).ConclusionFour-dimensional ultrasonography is superior than two-dimensional ultrasonography in terms of diagnosis the prenatal cleft lip and palate, it is a good method to approach the world.