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目的:验证伤寒脂多糖-被动血凝(LPS-PHA)诊断试剂的临床应用价值。方法:对210例疑似伤寒、副伤寒病人血清用LPS-PHA诊断试剂作快速诊断检测,并与血培养和伤寒血清凝集反应(肥达反应)作比较。结果:91例血培养伤寒或副伤寒杆菌阳性者伤寒LPS-PHA阳性77例(84.6%),肥达反应阳性66例(72.5%),血培养阳性者的LPS-PHA与肥达反应阳性率比较有统计学显著差异(P<0.05),特别是早期病人(病程在7天内)的阳性率(75.0%)显著高于肥达反应(33.3%)。结论:LPS-PHA诊断试剂对诊断伤寒、副伤寒优于肥达反应。
Objective: To verify the clinical value of LPS-PHA diagnostic reagent. Methods: 210 cases of suspected typhoid and paratyphoid patients serum LPS-PHA diagnostic reagent for rapid diagnosis and detection, and blood culture and typhoid serum agglutination (Waddy response) for comparison. Results: 91 cases of typhoid fever or paratyphoid fever-positive typhoid fever in 91 cases were positive in 77 cases (84.6%), and 66 cases (72.5%) were positive in fat-fed reaction. LPS-PHA and (P <0.05). The positive rate (75.0%) in early stage patients (within 7 days duration) was significantly higher than that of Widal response (33.3%). Conclusion: LPS-PHA diagnostic reagent is superior to Widal reaction in the diagnosis of typhoid and paratyphoid.