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柳胺苄心定(labetalol)是水杨酸氨衍生物,对α、β肾上腺素能受体有竞争性拮抗作用,对高血压患者无论立位、坐位、卧位均有降压作用。我院1986年2～6月,对31例中、重度妊高征患者,应用柳胺苄心定代替硫酸镁治疗,并观察药物的有效作用及对胎儿的影响,现报道如下。资料与方法本组系孕32～41~+周的中度或重度妊高征患者,其中2例为子痫、血压均超过140/100mmHg,部分有主诉及化验异常,年龄24～36岁,平均为28±3岁。症状与体征:头痛、头晕者15例(15/31),水肿11例(11/31),抽搐昏迷2例(2/31)。
Labetalol, a salicylic acid derivative of ammonia, is a competitive antagonist of alpha and beta adrenergic receptors and has antihypertensive effects in hypertensive patients regardless of standing position, sitting position or lying position. Our hospital from February 1986 to June, 31 cases of patients with moderate and severe pregnancy-induced hypertension, the application of liufacalin instead of magnesium sulfate treatment, and observe the effective effect of drugs and the impact on the fetus are reported below. Materials and Methods This group of 32 ~ 41 ~ + pregnant women with moderate or severe pregnancy-induced hypertension, of which 2 cases of eclampsia, blood pressure were more than 140 / 100mmHg, some complaints and laboratory abnormalities, aged 24 to 36 years old, The average was 28 ± 3 years old. Symptoms and signs: headache, dizziness in 15 cases (15/31), edema in 11 cases (11/31), convulsions coma in 2 cases (2/31).