论文部分内容阅读
目的:分析维吾尔族不同空腹血糖水平与冠状动脉病变程度的关系,探讨空腹血糖切点下调的意义。方法:回顾性分析321例拟诊冠心病于本院行冠状动脉造影的维吾尔族患者临床资料,依据空腹血糖水平分为4组:组1为空腹血糖<5.6 mmol/L;组2为5.6 mmol/L≤空腹血糖<6.1 mmol/L;组3为6.1 mmol/L≤空腹血糖<7.0mmol/L;组4为空腹血糖≥7.0 mmol/L),对不同空腹血糖下冠状动脉病变程度(病变支数,冠状动脉积分)进行分析。结果:校正年龄、性别、血脂紊乱等因素后,与组1比较,组2冠状动脉病变支数增加,差异有统计学意义(P<0.05),组3冠状动脉病变支数及冠状动脉病变总积分均明显增加,差异均有统计学意义(P<0.01)。结论:维吾尔族冠心病高危人群的冠状动脉病变程度随空腹血糖水平升高逐步加重,冠状动脉发生病变的风险自空腹血糖5.6~6.1 mmol/L阶段己开始明显增加。将空腹血糖的下限调整到5.6 mmol/L对预防心血管病变具有重要意义。
OBJECTIVE: To analyze the relationship between different fasting blood glucose levels and the degree of coronary artery lesion in Uygur nationality, and to explore the significance of down-regulation of fasting blood glucose point. Methods: The clinical data of 321 Uigur patients undergoing coronary angiography in our hospital were retrospectively analyzed. According to the fasting blood glucose level, the clinical data were divided into 4 groups: fasting blood glucose <5.6 mmol / L in group 1 and 5.6 mmol / L ≤ fasting blood glucose <6.1 mmol / L; group 3 6.1 mmol / L ≤ fasting blood glucose <7.0 mmol / L; group 4 fasting blood glucose ≥ 7.0 mmol / L), the degree of coronary artery lesions under different fasting glucose Count, coronary score) were analyzed. Results: After adjusting for age, gender, dyslipidemia and other factors, compared with group 1, group 2 coronary artery lesions increased, the difference was statistically significant (P <0.05), group 3 coronary artery lesions and coronary lesions Points were significantly increased, the difference was statistically significant (P <0.01). Conclusions: The severity of coronary lesions in the Uighur population at high risk of coronary heart disease gradually aggravates with the increase of fasting blood glucose level. The risk of coronary artery lesion has been significantly increased since 5.6 ~ 6.1 mmol / L fasting blood glucose level. Adjusting the lower limit of fasting plasma glucose to 5.6 mmol / L is important for the prevention of cardiovascular disease.