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目的:探析兰索拉唑治疗消化性溃疡的临床效果。方法:将70例消化性溃疡患者随机分成实验组和观察组,每组各35例。对实验组患者用兰索拉唑治疗,对照组用奥美拉唑治疗。对比两组患者的药物反应及产生的不良反应。结果:实验组和对照组患者消化性溃疡愈合率的比较差异具有统计学意义(P<0.05)。实验组患者幽门螺旋杆菌的根除率和对照组的比较差异具有统计学意义(P<0.05)。治疗一个月后,实验组患者症状消失32例,对照组患者症状消失25例,两组的比较差异具有统计学意义(P<0.05)。两组患者的药物不良反应发生率的无统计学意义(P>0.05)。结论:应用兰索拉唑能够使患者在较短时间内溃疡症状快速消失,溃疡愈合率较高,幽门杆菌的根除率高且不良反应轻微。
Objective: To investigate the clinical efficacy of lansoprazole in the treatment of peptic ulcer. Methods: Seventy patients with peptic ulcer were randomly divided into experimental group and observation group, 35 cases in each group. Patients in the experimental group were treated with lansoprazole and in the control group with omeprazole. The two groups of patients were compared for drug response and adverse reactions. Results: The healing rate of peptic ulcer in experimental group and control group was statistically significant (P <0.05). The eradication rate of Helicobacter pylori in the experimental group was significantly lower than that in the control group (P <0.05). One month after treatment, the symptoms in the experimental group disappeared in 32 cases, and the symptoms in the control group disappeared in 25 cases. The difference between the two groups was statistically significant (P <0.05). Two groups of patients with adverse drug reactions incidence was not statistically significant (P> 0.05). Conclusion: The application of lansoprazole in patients with a short period of time can make the symptoms of ulcers disappear rapidly, the healing rate of ulcers is higher, the eradication rate of H. pylori is high and the adverse reactions are slight.