作者以往报道蛛网膜下腔出血(SAH)病人的一级亲属比二级亲属和普通人口的SAH危险高3～7倍,而高血压部分原因是由遗传决定的。如果高血压促进了这一危险的增高,则SAH病人一级亲属中的高血压及其并发症的发生率应当比二级亲属高。基于此设想,作者对SAH病人一级亲属及二级亲属的高血压及其相关损害——卒中和冠心病的发生率做了前瞻性研究。 The authors previously reported that first-degree relatives of patients with subarachnoid hemorrhage (SAH) had a 3 to 7-fold higher risk of SAH than second-degree relatives and the general population, and that part of the cause of hypertension was genetically determined. If hypertension is contributing to this dangerous increase, hypertension and its complications in first-degree relatives of SAH patients should be higher than those of second-degree relatives. Based on this hypothesis, the authors prospectively studied the prevalence of stroke and coronary heart disease in patients with first-degree and second-degree relatives of hypertension in SAH and their related impairments.