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多年来,认为某些再障病例在发病机理上可能与骨髓的免疫抑制有关,故有人试用一些免疫抑制剂(如抗淋巴细胞球蛋白、抗人胸腺细胞球蛋白、甲基苄肼、环磷眺胺)来治疗再障而获一定效果。作者报告一例严重再障应用环磷酰胺后基本康复。患者为一22岁男性,有氯霉素及克林达霉素使用史。确诊时红细胞压积为14%,白细胞数1,700(中性白细胞8%),血小板数7,000,网织细胞0.3%。
Over the years, some patients with aplasia that the pathogenesis may be related to bone marrow immunosuppression, it was tried some immunosuppressive agents (such as anti-lymphocyte globulin, anti-human thymocyte globulin, procarbazine, Tuamine) to treat aplastic anemia and have a certain effect. The authors report a case of severe recovery of aplastic anemia after basic recovery of cyclophosphamide. The patient was a 22-year-old male with history of chloramphenicol and clindamycin use. The diagnosed hematocrit was 14%, the number of white blood cells was 1,700 (neutrophils 8%), the number of platelets was 7,000, and the number of reticulocytes was 0.3%.