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目的 探讨罗哌卡因与芬太尼联合自控硬膜外分娩镇痛的效果及对母儿的影响。方法 选择自愿要求分娩镇痛的480例产妇为镇痛组,以同期未实行分娩镇痛的480例产妇为对照组。比较两组产妇分娩时镇痛效果、产程时间、剖宫产率、缩宫素使用、新生儿窒息及产后出血情况。结果 镇痛组视觉模拟评分法(Visual Analogue Scale/Score,VAS)评分明显低于对照组(P<0.05),第一产程缩短、剖宫产率低,与对照组比较差异有统计学意义(P<0.05),但增加了缩宫素使用,两组新生儿窒息、产后出血量比较差异无统计学意义(P>0.05)。结论 罗哌卡因与芬太尼联合自控硬膜外分娩镇痛效果好,对母婴无不良影响,满足整个产程的需要,值得临床进一步推广应用。
Objective To investigate the effect of combined epidural analgesia with ropivacaine and fentanyl on maternal and childbirth. Methods 480 pregnant women who volunteered for labor analgesia were selected as the analgesic group and 480 pregnant women who did not undergo labor analgesia during the same period as the control group. The analgesic effect, labor duration, cesarean section rate, oxytocin use, neonatal asphyxia and postpartum hemorrhage were compared between the two groups. Results Visual analogue scale (VAS) score of the analgesic group was significantly lower than that of the control group (P <0.05), the first stage of labor was shortened, the rate of cesarean section was low, the difference was statistically significant compared with the control group P <0.05), but increased the use of oxytocin, two groups of neonatal asphyxia, postpartum hemorrhage was no significant difference (P> 0.05). Conclusion The combination of ropivacaine and fentanyl in the control of epidural analgesia is effective and has no adverse effect on maternal and infant. It meets the needs of the entire labor and deserves to be further popularized and applied clinically.