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目的:观察高原地区丙种球蛋白治疗重症毛细支气管炎的疗效。方法:将高原地区重症毛细支气管炎46例随机分为治疗组和对照组。两组均给予抗感染、抗病毒、止咳、化痰、平喘、吸氧、糖皮质激素等综合治疗,治疗组在此基础上加用丙种球蛋白(IVIG)400mg/(kg/d)静点,3天为一疗程。对照组则不用IVIG治疗。治疗期间观察患儿发热、咳嗽、喘憋、肺部体征消失时间和并发症等。结果:两组咳嗽消失时间、肺部体征消失时间、平均住院时间比较有非常显著性差别(P<0.01)。结论:大剂量丙种球蛋白治疗高原地区重症毛细支气管炎效果确切。
Objective: To observe the efficacy of gamma globulin in treatment of severe bronchiolitis in the plateau. Methods: 46 cases of severe bronchiolitis in plateau were randomly divided into treatment group and control group. The two groups were given anti-infective, anti-virus, cough, phlegm, asthma, oxygen, glucocorticoid and other comprehensive treatment, the treatment group on this basis with the addition of gamma globulin (IVIG) 400mg / (kg / d) Point, 3 days for a course of treatment. The control group did not use IVIG treatment. Observation of children during treatment fever, cough, wheezing, lung signs disappear time and complications. Results: There was a significant difference between the two groups in the disappearance of cough, the disappearance of lung signs and the average hospital stay (P <0.01). Conclusion: High dose gamma globulin is effective in treating severe bronchiolitis in the plateau area.