学习了贵刊1991年第6卷第3期刊登的《速尿、多巴胺腹腔内注射治疗肝硬化顽固性腹水》一文后,启发很大,受益非浅。笔者自1991年5月～1994年4月在临床中使用速尿、多巴胺腹腔内注射治疗肝硬化顽固性腹水40例,取得了满意的效果,现报告如下。 1 资料 40例患者均系肝硬化失代偿期的病人,其中,肝炎后肝硬化32例,血吸虫病性肝硬化8例,男35例,女5例,年龄31～64岁,反复出现腹水时间4月～1年不等,且有35例患者在院外和入院后使用本疗法前均使用过各种利尿剂及多次抽腹水等综合治疗,腹水略有减少,但在短时间内腹水又增加。 2 方法 应用速尿40mg,多巴胺20mg于病人左下及右下腹腔交替注入,每日一次,同时,口服安体舒通40mg,一日三次,然后根据利尿反应和腹水消减情况,增加速尿和多巴胺的剂量,速尿的最大量为80mg,多巴胺60mg, Studied your magazine in 1991 Volume 6 No. 3 published in the “furosemide, intraperitoneal injection of dopamine treatment of cirrhosis refractory ascites” article, inspired a great benefit. The author from May 1991 to April 1994 in clinical use of furosemide, intraperitoneal injection of dopamine 40 cases of cirrhosis and refractory ascites, and achieved satisfactory results, are as follows. 1 data 40 patients were patients with decompensated liver cirrhosis, of which 32 cases of post-hepatitis cirrhosis, schistosomiasis cirrhosis in 8 cases, 35 males and 5 females, aged 31 to 64 years, repeated ascites Time from April to 1 year, and 35 patients in the hospital and after admission to the use of the therapy before the various diuretics and multiple ascites and other comprehensive treatment, a slight decrease in ascites, but in a short period of time ascites Increase again. 2 Methods Furosemide 40mg, 20mg of dopamine in patients with lower left and right lower abdominal cavity alternately injected once daily, and spironolactone 40mg, three times a day, and then according to the diuretic response and ascites reduction, increased furosemide and dopamine The maximum amount of furosemide 80mg, dopamine 60mg,