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以2,4-二氧六氢-1,3,5-三嗪为先导化合物,引入不同的酰基,进行N-酰化结构改造,合成了7个新化合物,抗病毒活性测试表明,其中4个化合物对TMV的抑制率达到50%~53%,与参照物DADHT接近.
Using 2,4-dioxo-1,3,5-triazine as the lead compound, different acyl groups were introduced and the N-acylation structure was modified to synthesize seven new compounds. The antiviral activity test showed that 4 The inhibition rate of the compounds to TMV reached 50% ~ 53%, which was close to the reference DADHT.