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环鸟苷酸磷酸二酯酶是感受器进行光传导过程中的关键成分，也是近几年研究视网膜变性疾病中最引人注目的课题之一。本文从环鸟苷酸磷酸二酯酶在光传导过程中的生理机制、rd小鼠视网膜的生化分析及基因突变、转基因rd／rd小鼠、环鸟苷酸磷酸二酯酶的编码基因及其在组织细胞中的表达、调控、用于检测视网膜色素变性患者的基因突变等方面，较全面地总结了近几年对视网膜环鸟苷酸磷酸二酯酶的研究进展。
Cyclic guanylate phosphodiesterase is a key component in the photoreceptors’ process of photoreceptors. It is also one of the most striking topics in the study of retinal degenerative diseases in recent years. This article from the cyclic mechanism of cyclic guanosine monophosphate phosphodiesterase in the process of light conduction, rd mouse retinal biochemical analysis and gene mutation, transgenic rd / rd mice, cyclic guanylate phosphodiesterase gene and its In tissue cells in the expression and regulation, for the detection of gene mutations in patients with retinitis pigmentosa, etc., a more comprehensive summary of the recent research progress of cyclic retinoic acid phosphodiesterase.