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９对狗作头部交叉循环，４对狗作脑交叉循环后，股动脉失血使平均动脉压（ＭＡＰ）降至５．３３ｋＰａ左右，维持３０ｍｉｎ。从其中一只狗（Ａ狗）股静脉输入占总失血量１０％的７．５％ＮａＣｌ溶液（实验组），或生理盐水（对照组）；另一只狗（Ｂ狗）不作任何处理。结果：实验组Ａ，Ｂ两狗动脉血压（ＡＰ）均显著回升，并维持至输液后６０ｍｉｎ，其中收缩压（ＳＰ）回升幅度大于舒张压（ＤＰ），脉压（ＰＰ）加大。对照组ＡＰ回升值无统计学意义。实验组及对照组心率（ＨＲ）均无明显变化。动脉血红细胞比容皆下降，但其下降值组间比较，Ｐ＞０．０５。实验组Ａ狗血浆钠有意义地增高，Ｐ＜０．０１；Ｂ狗变化同对照组。结果提示：在７．５％ＮａＣｌ溶液恢复失血性低血压的作用机制中，中枢神经系统起重要作用。
9 dogs for head cross-circulation, 4 pairs of dogs for brain cross-circulation, femoral artery blood loss so that mean arterial pressure (MAP) dropped to 5.33kPa, for 30min. A 7.5% NaCl solution (experimental group) or saline (control group), which accounted for 10% of the total blood loss, was injected into the femoral vein of one dog (dog) without any treatment. Results: The arterial blood pressure (AP) of A and B dogs in experimental group rebounded significantly and remained 60 minutes after infusion. The recovery of systolic pressure (SP) was greater than that of diastolic pressure (DP) and pulse pressure (PP). The control group AP return value was not statistically significant. Heart rate (HR) in experimental group and control group had no significant change. Arterial hematocrit decreased, but the decline between the values of the two groups, P> 0.05. Experimental group A dog plasma sodium increased significantly, P <0.01; B dog changes with the control group. The results suggest that central nervous system plays an important role in the mechanism of hemorrhagic hypotension restored by 7.5% NaCl solution.