目的探讨宫颈病变与年龄及症状、体征的关系。方法回顾性分析2010年1月—2012年12月在湖北省泾阳县医院行宫颈环形电切术(loop eelectrosurgical excision procedure,LEEP)391例患者的病史特点,包括年龄、症状、体征。结果 391例患者LEEP术后病理结果:308例为慢性宫颈炎宫颈息肉等,83例病理诊断为阳性,其中包括宫颈上皮内瘤样病变(cervical intraepithelial neoplasia,CIN)Ⅰ级25例,Ⅱ级26例,Ⅲ级28例及宫颈鳞癌4例。分析年龄与宫颈病变的关系显示年龄小于30岁组发病率为15.7%,较30岁以上组为低。不同临床症状的宫颈病变发病率之间差异无统计学意义(χ2=7.09,P>0.05)。单纯宫颈息肉样赘生物病理阳性率仅3.0%(2/66),宫颈光滑者病理阳性率高达27.3%(9/34),与宫颈糜烂的阳性率差异无统计学意义(χ2=0.529,P>0.05)。结论宫颈癌及癌前病变有年轻化趋势,好发于30岁以后妇女;宫颈病变及宫颈癌缺乏特征性临床表现,即使无临床表现者亦有一定的发病率,临床上应加大对高危人群的普查力度。 Objective To investigate the relationship between cervical lesions and age, symptoms and signs. Methods The clinical features of 391 patients with LEEP from January 2010 to December 2012 in Jingyang County Hospital of Hubei Province were retrospectively analyzed. The patients’ age, symptoms and signs were analyzed retrospectively. Results Pathological results of LEEP in 391 patients: 308 cases of chronic cervicitis and cervical polyps, 83 cases of pathological diagnosis were positive, including cervical intraepithelial neoplasia (CIN) Ⅰ grade 25 cases, Ⅱ grade 26 Cases, Ⅲ grade 28 cases and cervical squamous cell carcinoma in 4 cases. Analysis of the relationship between age and cervical lesions showed that the incidence of age less than 30 years old group was 15.7%, lower than the group over 30 years old. There was no significant difference in the incidence of cervical lesions between different clinical symptoms (χ2 = 7.09, P> 0.05). The pathological positive rate of simple cervical polyposis-like neoplasms was only 3.0% (2/66), and the positive rate of cervical smooth pathology was as high as 27.3% (9/34), with no significant difference with the positive rate of cervical erosion (χ2 = 0.529, P > 0.05). Conclusions Cervical cancer and precancerous lesions have a tendency of getting younger, which occurs in women after 30 years of age. Cervical lesions and cervical cancer lacks characteristic clinical manifestations, and even if there is no clinical manifestation, there is a certain incidence rate, which should be increased clinically Crowd census efforts.