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在62例慢性乙型肝炎(乙肝)患者中,38例(治疗组)接受重组α-2b干扰素治疗,24例(对照组)接受抗乙肝免疫核糖核醚治疗。结果表明,治疗组HBeAg和HBVDNA清除率明显高于对照组(P<0.05),血清ALT水平明显升高的患者(ALT>70U)及慢性活动型肝炎患者对干扰素的治疗反应明显优于ALT正常及慢性迁延型肝炎病人(P<0.05)。
Of the 62 patients with chronic hepatitis B (hepatitis B), 38 (treatment group) received recombinant interferon alpha-2b and 24 (control group) received anti-hepatitis B immunosuppressive therapy. The results showed that the treatment group HBeAg and HBVDNA clearance rate was significantly higher than the control group (P lt; 0.05), serum ALT levels significantly elevated patients (ALT> 70U) and chronic active hepatitis patients response to interferon was significantly better In ALT patients with normal and chronic persistent hepatitis (P <0.05).