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目的 探讨脉冲振荡法对儿童肺功能检测特别是哮喘的应用价值。方法 采用脉冲振荡法,对哮喘发作组121 例、哮喘缓解组147 例患儿和正常对照组217 例进行肺功能测定,组间比较5Hz 时、20 Hz 时的气道阻力(R5、R20)、肺弹性阻力(X5)、和共振频率(Fres),并长期咳嗽组102 例进行肺功能测定,对其中气道阻力增高者加做支气管扩张试验。结果 哮喘发作组R5 10-2 hPa/(L·s),R206-6 hPa/(L·s),X5 -4-4 hPa /(L·s) ,Fres23-7 Hz,对照组R5 7-1 hPa/(L·s) ,R20 5-0 hPa/(L·s) ,X5 -2-5hPa/(L·s) ,Fres19-0 Hz,两组比较差异有显著意义( P< 0-01);哮喘缓解组与发作组比较已有显著改善( P< 0-01) ,但气道阻力值仍高者占40-1% ;长期咳嗽组中有38 例气道阻力增高,均做支气管扩张试验,其中21 例阳性,结合临床明确哮喘的诊断。结论 脉冲振荡法可以作为儿童肺功能检测和小儿哮喘诊断及治疗监测的方法
Objective To investigate the value of pulse oscillation method in detection of pulmonary function in children, especially asthma. Methods Pulmonary function was measured in 121 cases of asthma attack group, 147 cases of asthma remission group and 217 cases of normal control group by pulse oscillation method. Airway resistance (R5, R20) at 20 Hz was compared between groups at 5 Hz. Lung resistance (X5), and resonance frequency (Fres). Long-term cough group (n = 102) was used for pulmonary function test. Bronchodilator test was performed on those with increased airway resistance. Results In the asthma attack group, R5 10-2 hPa / (L · s), R206-6 hPa / (L · s), X5-4-4 hPa / (L · s), Fres23-7 Hz, R5- The differences between the two groups were statistically significant (P <0-P <0). The difference between the two groups was significant (P <0- 01); asthma relief group and the attack group has been significantly improved (P <0-01), but still high airway resistance value accounted for 40-1%; long-term cough group, 38 cases of airway resistance increased, are done Bronchiectasis test, of which 21 were positive, combined with the diagnosis of clinically clear asthma. Conclusion Pulsed Oscillation can be used as a method to monitor the diagnosis and treatment of childhood pulmonary function and pediatric asthma