消化性溃疡并出血是消化道出血中最常见的病因。溃疡病的出血发生率约为20％。(1)药物治疗可以促进止血,其中胃酸抑制剂的使用是止血治疗最重要的环节。目前临床最常用的有H2受体拮抗剂及质子泵抑制剂,如何选用这两类药物是临床医师常遇到的问题之一。我们观察了240例消化性溃汤并出血的患者使用这两类药物的具体情况,进行了全面的回顾性分析,以提高认识。 Peptic ulcer bleeding is the most common cause of gastrointestinal bleeding. The incidence of ulcer bleeding is about 20%. (1) drug therapy can promote hemostasis, in which the use of gastric acid inhibitors is the most important part of hemostasis. Currently the most commonly used clinical H2 receptor antagonists and proton pump inhibitors, how to choose these two types of drugs is one of the problems often encountered by clinicians. We looked at 240 patients with digestive ulcer bleeding and the use of these two types of drugs in the specific circumstances, conducted a comprehensive retrospective analysis to raise awareness.