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我们对呼和浩特地区居住的38名病毒性肝炎的患者和60名健康献血员进行了人体白细胞抗原与肝炎病的关联研究。发现甲型病毒性肝炎病人的HLA-A_1及HLA-B_5抗原频率高于对照组;乙型病毒性肝炎病人的HLA-B_8和HLA-Bw_(35)及HLA-Cw7抗原频率高于对照组。在统计学上呈显著相关关系,它们的相对危险度[RR]在3～9之间。本文的研究为肝炎病因学的研究提供了新的内容,由于病毒性肝炎与人类白细胞的关联受很多因素的影响,而且在此方面的报导结果又各不相同,所以对此还需进一步地研究和探讨。
We conducted a study on the association of human leukocyte antigen with hepatitis in 38 patients with viral hepatitis living in Hohhot and 60 healthy blood donors. The frequencies of HLA-A 1 and HLA-B 5 antigens in patients with type A viral hepatitis were higher than those in controls. The frequencies of HLA-B 8, HLA-Bw 35 and HLA-Cw 7 antigens in patients with hepatitis B were higher than those in controls. Statistically significant correlation, their relative risk [RR] in the 3 to 9 between. The research in this article provides new contents for the study of etiology of hepatitis. Since the relationship between viral hepatitis and human leucocytes is affected by many factors, and the results reported in this area are different, so further study is needed And explore.