Studying the equation of state of asymmetric nuclear matter by proton-rich reaction expands the methods of symmetry energy studies. Also the formed proton-rich matter can be used to check the theory of nuclear matter. One generally thinks that proton-rich reactions are not very suitable to study nuclear symmetry energy owing to stronger Coulomb effects. Studying the equation of state of asymmetric nuclear matter by proton-rich reaction expands the methods of symmetry energy studies. Also the formed proton-rich matter can be used to check the theory of nuclear matter. One generally thinks that proton-rich reactions are not very suitable to study nuclear symmetry energy owing to stronger Coulomb effects.