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本文比较急性心肌梗塞患者快速静脉注入大剂量(2mg/kg)和标准剂量(1.25mg/kg)组织型纤溶酶原激活剂(rt-PA)之后90mim 梗塞区供血冠(状动)脉畅通率和出血并发症发生率。175例急性心肌梗塞患者参加多中心试验,随机分成两组。A 组84例给予大剂量 rt-PA,在头1h 内静脉给予1.2mg/kg(其中10％剂量首先静脉推注),在后2h 内静脉给予0.8mg/kg。B 组91例给予标准剂量 rt-
In this paper, 90mim infarction area blood supply to the coronary artery (ACF) after rapid intravenous infusion of high dose (2mg / kg) and standard dose (1.25mg / kg) tissue plasminogen activator (rt-PA) in patients with acute myocardial infarction Rate and bleeding complication rate. A total of 175 patients with acute myocardial infarction participated in a multicenter trial and were randomized into two groups. A group of 84 patients given high-dose rt-PA, intravenous 1.2mg / kg within the first 1h (10% of the dose of the first intravenous injection), within 2h after intravenous administration of 0.8mg / kg. 91 cases in group B were given standard dose rt-