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[目的]观察辨证分型联合西药治疗慢性萎缩性胃炎疗效。[方法]使用随机平行对照方法,将60例门诊患者按病志号抽签法简单随机分为两组。对照组30例雷贝拉唑,10mg/次,2次/d;克拉霉素,0.5g/次,2次/d;阿莫西林,1g/次,2次/d;果胶铋,150mg/次,3次/d。治疗组30例辨证分型:肝胃不和-柴胡疏肝散(柴胡、白芍各15g,香附12g,川芎、陈皮、枳壳、木香各10g,甘草5g);脾胃虚寒-补中益气汤(黄芪24g,生山药20g,党参、白术、茯苓各15g,白芍12g,陈皮、莪术各10g,甘草、柴胡、木香、防风各6g);肝胃郁热-三仁汤(薏苡仁30g,白豆蔻仁、厚朴、法半夏、茯苓各15g,杏仁、竹叶、黄连各10g);胃络瘀阻-丹参饮(丹参20g,川芎、赤芍各15g,砂仁、牡丹皮各10g,甘草5g);1剂/d,水煎400m L,早晚口服,200m L/次;西药治疗同对照组。连续治疗90d为1疗程。观测临床症状、黏膜炎症、幽门螺杆菌清除率、不良反应。治疗1疗程,判定疗效。[结果]治疗组显效18例,有效10例,无效2例,总有效率93.33%。对照组显效12例,有效9例,无效9例,总有效率70.00%。治疗组疗效优于对照组(P<0.05)。幽门螺杆菌清除率治疗组高于对照组(P<0.05)。[结论]辨证分型联合西药治疗慢性萎缩性胃炎疗效满意,无严重不良反应,值得推广。
[Objective] To observe the curative effect of syndrome differentiation and western medicine on chronic atrophic gastritis. [Methods] Using randomized parallel control method, 60 cases of outpatients were randomly divided into two groups randomly according to the method of drawing lots of patients’ disease. Control group 30 rabeprazole, 10mg / times, 2 times / d; clarithromycin, 0.5g / times, 2 times / d; amoxicillin, 1g / times, 2 times / / Times, 3 times / d. Treatment group, 30 cases of syndrome differentiation: liver and stomach - Chaihu Shugan San (Bupleurum, white peony root of each 15g, Cyperus rotundus 12g, Chuanxiong, Citrus, Citrus aurantium, licorice 10g, licorice 5g) - Bu Zhong Yi Qi Tang (Astragalus 24g, raw yam 20g, Codonopsis, Atractylodes, Poria 15g, white peony root 12g, dried tangerine peel, Curcuma the 10g, licorice, Bupleurum, Ren Tang (Yiyiren 30g, white cardouren, Magnolia, Pinellia, Poria 15g, almonds, bamboo leaves, Coptis 10g); Stomach collaterals - Danshen drink (Salvia 20g, Chuanxiong, red peony 15g, Amomum, moutan each 10g, licorice 5g); 1 / d, decoction 400m L, morning and evening oral, 200m L / times; Western medicine treatment with the control group. Continuous treatment of 90d for a course of treatment. Observation of clinical symptoms, mucosal inflammation, Helicobacter pylori clearance, adverse reactions. Treatment of a course of treatment to determine the efficacy. [Result] In the treatment group, 18 cases were markedly effective, 10 cases were effective and 2 cases were ineffective. The total effective rate was 93.33%. The control group markedly effective in 12 cases, effective in 9 cases, ineffective in 9 cases, the total effective rate was 70.00%. The treatment group was better than the control group (P <0.05). Helicobacter pylori clearance rate in the treatment group was higher than that in the control group (P <0.05). [Conclusion] Syndrome differentiation combined with Western medicine in the treatment of chronic atrophic gastritis with satisfactory results, no serious adverse reactions, it is worth promoting.