The content of lymphocytic and erythrocytic K -, Na- , Ca++, Mg++ changed in patients with congestive heart failure, related to clinical treatment and prognosis. The longer the course of disease, the more significant the changes, with no relation to the etiology of heart disease. The changes were partically improved after treatment of the heart failure. The content of electrolytes is not significantly different in patients in NYHA Class Ⅲ, compared to those in NYHA Class Ⅳ. The metabolic changes of electrolytes occur on the myocardial cells, skeletal muscle cells and peripheral erythrocytes in patients with congestive heart failure. However, serum electrolyte content does not reflect precisely overall electrolyte metabolism in the body. Whether similar, changes of electrolyte content occur in the peripheral lymphocytes is rarely reported. We studied the lymphocytic and erythrocytic electrolyte content in patients with congestive heart failure, to provide some reference in the clinical treatment and pr The content of lymphocytic and erythrocytic K-, Na-, Ca ++, Mg ++ changed in patients with congestive heart failure, related to clinical treatment and prognosis. The longer the course of disease, the more significant the changes, with no relation to the etiology of The changes were partically improved after treatment of the heart failure. The content of electrolytes is not significantly different in patients in NYHA Class III, compared to those in NYHA Class IV. The metabolic changes of electrolytes occur on the myocardial cells, skeletal However, serum electrolyte content does not reflect precisely positive electrolyte metabolism in the body. However similar changes in electrolyte content occur in the peripheral lymphocytes are rarely reported. We studied the lymphocytic and erythrocytic electrolyte content in patients with congestive heart failure, to provide some reference in the clini cal treatment and pr