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近年发现庆大霉素可导致急性肾功能衰竭,本文报告5例患者,2女1男。因持续发热、畏寒,经肌注庆大霉素24～32万u/日,先后于第3～17天出现尿少、尿痛至尿闭而入院。体检:3例患者心肺无异常,一侧或两侧肾区有叩击痛;临床均有少尿、肾小管蛋白、管型尿、轻度糖尿、尿比重及尿渗透压偏低等。给予控制入水量,静滴甘露醇、654—2、速尿、能量合剂、肌苷等综合治疗,三周后,尿常规除1例比重1.014外,余为正常,患者症状好转出院。另2例患者(1男1女),因畏寒发
In recent years, found that gentamicin can cause acute renal failure, this report 5 patients, 2 female 1 male. Due to persistent fever, chills, intramuscular injection of gentamicin 24 ~ 320000 u / day, has appeared in the first 3 to 17 days less urine, dysuria to the urine closed and admitted to hospital. Physical examination: No abnormality of heart and lung in 3 patients. Percussion pain in kidney area of one or both sides; oliguria, tubular protein, tubular urine, mild diabetes mellitus, urinary specific gravity and low urine osmotic pressure were all found in clinic. Given control of water intake, intravenous infusion of mannitol, 654-2, furosemide, energy mixture, inosine and other comprehensive treatment, three weeks later, except for 1 case of urinary specific gravity of 1.014, I was normal, the patient improved symptoms discharged. The other 2 patients (1 male and 1 female), because of chills