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目的 :探讨社区获得性感染病例抗微生物药物应用情况。方法 :对 2 0 0 3年 1～ 6月入住浙江大学医学院附属第一医院呼吸内科病房的社区获得性感染患者 2 0 0例应用抗微生物药物进行统计分析。结果 :社区获得性感染患者 2 0 0例中 ,抗微生物药物使用频度从高到低依次为头孢哌酮 /舒巴坦、左氧氟沙星片、左氧氟沙星注射液。涉及 5 5种抗微生物药物。平均每例使用抗微生物药物 (3 .6± 2 .0 )种。在限定日剂量 (DDDs)排序中前 3位抗微生物药物分别为左氧氟沙星片、头孢哌酮 /舒巴坦、左氧氟沙星注射液。每天药费消耗针剂大于片剂。结论 :该院抗微生物药物使用基本合理 ,但亦存在同类药物联合应用等不合理用药现象 ,应进一步加强抗微生物药物的合理应用。
Objective: To investigate the use of antimicrobials in community-acquired infections. Methods: From January to June 2003, 200 patients with community-acquired infections admitted to the Respiratory Medicine Ward of the First Affiliated Hospital of Medical College of Zhejiang University were enrolled in the study. The antimicrobial agents were statistically analyzed. Results: Of the 200 community-acquired infections, the frequency of antimicrobial use was cefoperazone / sulbactam, levofloxacin and levofloxacin in descending order. Involving 55 antimicrobial drugs. On average, antimicrobials (3.66 ± 2.0) were used in each case. The top three antimicrobials in the defined daily dose (DDDs) rankings were levofloxacin tablets, cefoperazone / sulbactam, and levofloxacin injection, respectively. Daily medication costs more than tablets. Conclusion: The hospital use of antimicrobial drugs is reasonable, but there are also the phenomenon of unreasonable use of drugs such as joint application of drugs should be further strengthened the rational application of antimicrobial drugs.