日前,国家药品不良反应监测中心发布的《药品不良反应信息通报》称,在全球已上市20余年、用于治疗痤疮及角化异常性疾病的异维A酸,可导致罕见且严重的皮肤损害。近期,国外药品管理部门发布了有关使用异维A酸口服制剂引起严重皮肤损害的安全性信息。罗氏公司发现了 Recently, the National Adverse Drug Reaction Monitoring Center released the “Adverse Drug Reaction Bulletin,” said that in the world has been listed for more than 20 years, for the treatment of acne and keratosis abnormalities of isotretinoin, can cause rare and serious skin damage . Recently, foreign drug administrations released safety information on the use of isotretinoin oral preparations causing severe skin damage. Roche discovered