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本实验通过测定巨噬细胞存活率和超氧阴离子自由基，研究了桦木尘的细胞毒作用。结果表明：随桦木尘剂量的增大和接触时间的延长其细胞毒作用逐渐增强（Ｐ＜０．０５）；而超氧阴离子自由基的产生则随之增多（Ｐ＜０．０５）。两者的变化在一定接尘时间内呈负相关关系。实验中发现，超氧阴离子自由基产生的增加先于巨噬细胞存活率的下降。提示：桦木尘的毒作用可能与超氧阴离子自由基产生过度有关。
In this experiment, the cytotoxicity of birch dust was studied by measuring the survival rate of macrophages and superoxide anion free radicals. The results showed that the cytotoxicity gradually increased with the increase of dose of birch dust and prolongation of contact time (P <0.05), while the production of superoxide anion radical increased (P <0.05). Both changes in a certain period of dust was negatively correlated. It was found in experiment that the increase of superoxide anion radical generation preceded the decrease of macrophage survival rate. Tip: The toxic effect of birch dust may be related to the excessive generation of superoxide anion radicals.