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作者于1983～1993年在意大利南部两个人口统计学、种族和生活方式相同的乙型肝炎高发的城镇,完成了两种不同的乙型肝炎疫苗接种计划,即对婴儿和12岁儿童实行普种及对高危人群接种。本文评价了乙型肝炎疫苗接种对每个城镇总人群中乙型肝炎流行状况的影响,并比较了两种接种策略的效果。 作者于1983～1987年对母亲HBsAg阳性的婴儿在0、1、2及14月龄接种法国血源性乙型肝炎疫苗,剂量为5μg HBsAg。第1针在出生后1周内注射,并在出生后几小时内注射特异性免疫球蛋白(0.5ml/kg)。对母亲HB
The authors completed two different hepatitis B vaccination programs in 1983 and 1993 in two towns in southern Italy with the highest demographics, ethnicity, and lifestyle of hepatitis B vaccination: infants and 12-year-olds Species and vaccination of high-risk groups. This article assesses the impact of hepatitis B vaccination on the prevalence of hepatitis B in the general population in each town and compares the effects of both vaccination strategies. The authors vaccinated mothers with HBsAg-positive infants at 0, 1, 2, and 14 months of age from 1983 to 1987 at a dose of 5 μg of HBsAg. The first needle is injected within 1 week after birth and the specific immunoglobulin (0.5 ml / kg) is injected within a few hours after birth. To mother HB