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本文比较了生活在冷室（５±１℃，２０只）和暖室（２０±３℃，３５只）达三周的雄性Ｗｉｓｔａｒ大鼠下丘脑脑片视前区神经元电活动和温度敏感性，共记录到１２７个来自暖室组及８６个来自冷室组自发放电神经元。结果表明：（１）冷适应后冷敏神经元的比例明显提高，温度敏感性不变而放电活动的临界温度和下限温度明显下移；（２）热敏神经元的温度敏感性和临界温度降低，但在３７℃时的自发放电活动频率显著增加；（３）非温敏神经元的电活动也增加，其下限温度下移极显著，显示了大鼠视前区神经元在冷适应中的可塑性及其与冷适应中体温调节的机制相关。
In this study, we compared the electrical activity and temperature sensitivity of neurons in the preoptic hypothalamus of male Wistar rats living in cold room (5 ± 1 ℃, 20) and warm room (20 ± 3 ℃, 35) for three weeks A total of 127 self-discharge neurons were recorded from the greenhouse group and 86 from the cold room group. The results showed that: (1) the proportion of cold sensitive neurons increased significantly after cold acclimation, while the temperature sensitivity remained unchanged and the critical temperature and minimum temperature dropped significantly. (2) The temperature sensitivity and critical temperature (3) The electrical activity of non-temperature-sensitive neurons also increased, and its lower limit temperature down significantly, indicating that the preoptic neurons in the cold adaptation Plasticity and its mechanism of thermoregulation in cold adaptation.