成纤维细胞生长因子-23(fiborblast growth factor-23,FGF-23)是近年来发现的一种新型调节钙磷代谢的细胞因子。许多研究证明,FGF-23是X连锁低磷血症佝偻病(X-linked hypophosphatemic rickets,XLHD)、常染色体显性遗传性低磷血症性佝偻病(autosomal dominant hypophosphatemicrickets,ADHR)和肿瘤性骨软化症(tumor-induced osteomalacia,TIO)等的共同致病因子。FGF-23不仅在钙磷代谢中起 Fibroblast growth factor-23 (FGF-23) is a new type of cytokines that regulate the metabolism of calcium and phosphorus in recent years. Numerous studies have demonstrated that FGF-23 is a common cause of X-linked hypophosphatemic rickets (XLHD), autosomal dominant hypophosphatemic rickets (ADHR) and osteomalacia (tumor-induced osteomalacia, TIO) and other common virulence factors. FGF-23 plays not only in the metabolism of calcium and phosphorus