心衰的治疗以往一直是用强心利尿剂,近来重视了血管扩张剂作为重度和难治性心衰的治疗措施之一。最近研究清楚了在交感神经末稍的突触,突触前存在α_2受体,与调节去甲肾上腺素有关,如酚妥拉明和苯氧苄胺等阻滞突触前α_2受体,结果促进去甲肾上腺素的释放;突触后α_1受体阻滞剂则 Treatment of heart failure In the past has been the use of cardiac diuretics, has recently emphasized the use of vasodilators as a treatment for severe and refractory heart failure. Recently, it has been clarified that the presence of α_2 receptors in presynaptic and presynaptic sympathetic terminals is closely related to the regulation of norepinephrine, such as blockade of presynaptic α_2 receptors such as phentolamine and phenoxybenzamine, Norepinephrine release; postsynaptic α_1 receptor blockers then