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目的:探讨急性有机磷农药中毒的有效治疗方法及效果。方法:将我院2013年1月至2013年12月收治的50例急性有机磷农药中毒的患者随机分为观察组和对照组,每组25例,对照组采用阿托品治疗,观察组采用长托宁治疗,比较两组的治疗效果及不良反应。结果:观察组的阿托品用量少于对照组,起效时间、症状消失时间、全血胆碱酯酶(Ch E)活性恢复正常时间、住院时间均短于对照组,中间综合征(ISM)的发生率、病死率低于对照组,有统计学意义(P<0.05)。两组的阿托品化时间无统计学意义(P<0.05)。观察组视力模糊、口干、心动过速等发生率均低于对照组,有统计学意义(P<0.05)。结论:长托宁能够有效提高急性有机磷农药中毒的治疗效果,减少阿托品的用量,降低病死率,减少药物使用的不良反应,值得推广。
Objective: To investigate the effective treatment of acute organophosphorus pesticide poisoning and its effects. Methods: Fifty patients with acute organophosphorus pesticide poisoning admitted to our hospital from January 2013 to December 2013 were randomly divided into observation group and control group, with 25 cases in each group. The control group was treated with atropine. The observation group was treated with long care Ning treatment, the two groups compared the treatment and adverse reactions. Results: The dosage of atropine in the observation group was less than that in the control group, the onset time, the disappearance of symptoms, the recovery of ChE activity, the length of stay in hospital were shorter than those in the control group, intermediate syndrome (ISM) The incidence of mortality was lower than the control group, with statistical significance (P <0.05). There was no significant difference in atropisation time between the two groups (P <0.05). The incidence of blurred vision, dry mouth and tachycardia in the observation group were lower than those in the control group, with statistical significance (P <0.05). Conclusion: Penehyclidine can effectively improve the therapeutic effect of acute organophosphorus pesticide poisoning, reduce the dosage of atropine, reduce the mortality and reduce the side effects of drug use, which is worth to be popularized.