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目的探讨梗阻性黄疸术后急性肾功能衰竭的相关影响因素。方法 82例梗阻性黄疸患者,按照是否出现急性肾功能衰竭分为肾衰竭组及无肾衰竭组,比较2组年龄、术前肾功能、肝功能、手术时间、出血量、有无胆道感染;采用logistic回归分析的方法,探讨梗阻性黄疸术后,出现急性肾功能衰竭的相关性因素。结果 82例梗阻性黄疸患者,有7例术后发生急性肾功能衰竭,发生率为8.54%,2组患者术前肾功能均在相同水平;肾衰竭组患者谷氨酰基转肽酶(55.4±23.7)mmol/L、总胆红素(313.2±48.2)mmol/L、手术时间(5.6±0.9)h、出血量(800.5±100.7)ml、术前胆道感染6例,均高于无肾衰竭组,差异有统计学意义(P<0.05),经logistic回归分析,患者年龄、谷氨酰基转肽酶、总胆红素、手术时间、出血量、术前有无胆道感染,与患者急性肾功能衰竭有显著相关性(P<0.05)。结论年龄、术前肝功能、手术时间、出血量、术前有无胆道感染,是梗阻性黄疸术后出现急性肾功能衰竭的重要影响因素。
Objective To investigate the related factors of postoperative acute renal failure in patients with obstructive jaundice. Methods Eighty - two patients with obstructive jaundice were divided into renal failure group and non - renal failure group according to whether there was acute renal failure. The age, preoperative renal function, liver function, operation time, blood loss and biliary tract infection were compared. Logistic regression analysis was used to explore the related factors of acute renal failure after obstructive jaundice. Results 82 cases of obstructive jaundice, 7 cases of acute renal failure occurred after the operation, the incidence was 8.54%, two groups of patients with the same level of preoperative renal function; patients with renal failure glutamyl transpeptidase (55.4 ± 23.7) mmol / L, total bilirubin (313.2 ± 48.2) mmol / L, operation time (5.6 ± 0.9) h, blood loss (800.5 ± 100.7) ml and preoperative biliary tract infection were all higher than those without renal failure Group, the difference was statistically significant (P <0.05), by logistic regression analysis, the patient’s age, glutamyl transpeptidase, total bilirubin, operation time, blood loss, preoperative and without biliary tract infection, and patients with acute kidney There was a significant correlation between failure and failure (P <0.05). Conclusion Age, preoperative liver function, operation time, blood loss, and the presence or absence of biliary tract infection before operation are the important factors that cause postoperative acute renal failure in patients with obstructive jaundice.