近40年来,黑色素瘤的发生率逐年增高,虽然早期诊断得到了发展,但估计在美国去年还是约有7 000多患者死于转移性黑色素瘤,氮烯咪胺(DTIC)是治疗转移性黑色素瘤最有效的药物,但其总有效率只有24％,与其它药物联用也不过30％～50％,并且常发生毒性反应。 作者研究了约2 500种植物提取物的抗 Over the past 40 years, the incidence of melanoma has been increasing year by year. Although early diagnosis has progressed, it is estimated that in the United States, about 7,000 patients died of metastatic melanoma in the past year. Nicladamine (DTIC) is used to treat metastatic melanin. The tumor is the most effective drug, but its total effective rate is only 24%, but it is only 30% to 50% in combination with other drugs, and toxic reactions often occur. The authors studied the resistance of about 2 500 plant extracts