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目的：为探讨听性脑干反应（ＡＢＲ） 对脑干放射性损害的诊断价值。方法：对放射性脑干脊髓病６ 例（１２ 耳） 、放疗后１ 年的鼻咽癌（ＮＰＣ） 患者１８ 例（３６ 耳） 和正常对照１５例（３０ 耳） 进行了ＡＢＲ 检测。结果：①放射性脑干脊髓病６ 例均有ＡＢＲ 异常，主要表现有ⅠⅢ，ⅢⅤ及ⅠⅤ间期明显延长、未引出ＡＢＲ 或波Ⅰ以后各波消失；②ＮＰＣ 患者放疗后１ 年ⅢⅤ和ⅠⅤ间期均值较放疗前明显延长（ Ｐ＜ ０ ．０１） 。结论：ＡＢＲ 是检测脑干通路病变的敏感指标，对脑干放射性损害的诊断有一定意义。
Objective: To investigate the diagnostic value of auditory brainstem response (ABR) on radiation damage of brain stem. Methods: ABR was detected in 6 cases (12 ears) of radioactive brain stem myelopathy, 18 cases (36 ears) of nasopharyngeal carcinoma (NPC) one year after radiotherapy and 15 cases (30 ears) of normal control. Results: ① There were ABR abnormalities in 6 cases of radioactive brain stem myelopathy. The main manifestations were Ⅰ Ⅲ, Ⅲ Ⅴ and Ⅰ V interphase obviously prolonged, the wave disappeared after inducing ABR or wave Ⅰ; ②NPC patients after radiotherapy 1 The mean of inter-stage III-V and I-V was significantly longer than that before radiotherapy (P <0.01). Conclusion: ABR is a sensitive indicator of pathological changes in the brainstem pathway and has some significance for the diagnosis of brain stem radiation damage.