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目的探讨不同病因、疗法、伴多系统器官衰竭 (MSOF)和机体高低分解代谢对急性肾功能衰竭 (ARF)病死率的影响。方法回顾分析两家医院多年来收治 ARF患者的发病率 ,比较不同病因及高低分解型 ARF患者 MSOF发生率 ,肾功能恢复率及病死率 ,并比较用不同疗法治疗 ARF其肾功能恢复率及病死率。结果各科病因及高低分解型患者 MSOF发生率、肾功能恢复率及病死率均有显著性差异 (P均 <0 .0 5 ) ,各科病死率分别与其 MSOF发生率、合并脏器衰竭的数目呈显著正相关 ,不同疗法急性肾功能衰竭的病死率有显著性差异 ,手术治疗病死率最低。结论临床上对不同科各种病因的 ARF合理地采用不同治疗方法可降低病死率。高分解型 ARF患者应积极寻找并去除导致高分解代谢的原发病因 ,以期降低病死率
Objective To investigate the influence of different etiologies, therapies, multiple system organ failure (MSOF) and catabolism of body on the mortality of acute renal failure (ARF). Methods The incidences of ARF patients in two hospitals over the years were retrospectively analyzed. The incidence of MSOF, the recovery of renal function and the mortality of patients with ARF were compared between different etiologies and ARF patients. The recovery rate and mortality of ARF patients treated with different therapies were compared rate. Results There were significant differences in the incidence of MSOF, renal function recovery and mortality between different etiologies and patients with high and low decomposing type (all P <0.05). The mortality rates of all subjects were related to the incidence of MSOF, There was a significant positive correlation between the number of patients with acute renal failure of different therapies have significant differences in mortality, surgical treatment of the lowest mortality. Conclusion ARF of various etiologies in different families can be used clinically to reduce the case fatality rate by adopting different treatment methods. High-resolution ARF patients should actively look for and remove the leading cause of high catabolism, with a view to reducing mortality