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作者们收集了30例未经手术的听神经鞘膜瘤,另有1例系经手术切除。复习文献有关听神经鞘膜瘤的组织病理学的报告,只有极少数超过5例者。这30例标本中有9例系来自多发性神经纤维瘤病,其中有3例为双侧者,另二例双侧病例均遗失一侧的标本。30例患者的年龄为12~70岁,2/3病例为女性。女性的平均年龄为36岁,男性为44岁。标本用火棉胶包埋,切片厚度为25~32μm,用苏木素伊红染色。结果如下:有8例肿瘤局限于内耳道,其余22例为大的肿瘤。内耳道肿瘤中只有1例的耳蜗和前庭功能无损害。15例大的肿瘤(多发性神经纤维瘤病除外)中有3例肿瘤在内耳道中有一直径大于8mm之根蒂。大多数肿瘤似发源于前庭神经节,30例中有26例可以观察到该神经节的残余部分。按Antoni的
The authors collected 30 cases of un-surgical acoustic nerve sheath tumors, and another one was surgically removed. Review the literature on the histopathology report of acoustic nerve sheath tumors, only a handful of more than 5 cases. Nine of these 30 specimens were from multiple neurofibromatosis, 3 of which were bilateral, and the other two cases had bilateral specimens missing. Thirty patients were 12 to 70 years old and 2/3 were women. The average age of women is 36 and the number of men is 44. Specimens were embedded in collodion, and the thickness of the slices was 25-32 μm, and stained with hematoxylin and eosin. The results were as follows: Eight tumors were confined to the inner ear canal, and the remaining 22 were large tumors. Only 1 case of inner ear canal tumors had no damage to the cochlea and vestibular function. Three out of 15 large tumors (other than multiple neurofibromatosis) had a root pedicle larger than 8 mm in the internal ear canal. Most of the tumors appeared to originate from the vestibular ganglion, and 26 of the 30 patients could observe the remainder of the ganglion. By Antoni