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目的 探讨广州市妊娠妇女的输血传播病毒 (TTV )感染情况和 TTV透过胎盘屏障进入胎儿体内 (垂直传播 )的可能性。 方法 应用套式 PCR对 2 5 2例广州市孕妇及其新生儿的配对血清标本进行 TTV DNA扩增。 结果 39例孕妇血清和 4例新生儿脐血清检测出 TTV DNA,孕母TTV感染率为 15 .5 % ,母婴垂直传播率为 10 .2 %。 结论 妊娠妇女存在 TTV感染且可经胎盘传递给胎儿。
Objective To investigate the possibility of TTV infection in pregnant women and the passage of TTV into the fetus through the placental barrier (vertical transmission) in Guangzhou. Methods Tested PCR was used to amplify TTV DNA of 2552 paired serum samples from pregnant women and their newborns in Guangzhou. Results TTV DNA was detected in 39 cases of pregnant women and 4 cases of neonatal umbilical serum. The infection rate of TTV in pregnant women was 15.5%, and the rate of mother to child vertical transmission was 10.2%. Conclusion Pregnant women have TTV infection and can pass the placenta to the fetus.