论文部分内容阅读
目的观察高脂血症性胰腺炎(Hyper Lipidemic Pancreastitis,HLP)患者应用胰岛素联合丹参注射液治疗的临床效果。方法选取2014年2月—2016年3月HLP患者86例,按照随机数字表法分为联合组(胰岛素联合丹参注射液治疗,43例)与胰岛素组(单独给予胰岛素治疗,43例),比较两组治疗后临床疗效及症状改善情况(腹痛消失时间、腹部压痛缓解时间、胃肠功能恢复时间)。计数资料比较采用χ2检验,计量资料比较采用t检验,P<0.05表示差异有统计学意义。结果治疗后,联合组总有效率97.7%高于胰岛素组81.4%,比较差异有统计学意义(P<0.05)。联合组腹痛消失时间(3.87±0.18)d、腹部压痛缓解时间(4.95±1.34)d、胃肠功能恢复时间(3.98±0.21)d均明显低于胰岛素组[(8.54±1.47)、(8.79±2.20)、(6.75±1.33)d],组间比较差异有统计学意义(均P<0.05)。结论胰岛素联合丹参注射液治疗HLP临床疗效显著,腹痛、腹部压痛、胃肠功能恢复情况比较理想。
Objective To observe the clinical effect of insulin combined with Salvia miltiorrhiza injection in patients with hyperlipidemic pancreatitis (HLP). Methods Eighty-six patients with HLP between February 2014 and March 2016 were selected and divided into three groups according to the random number table: combination group (insulin combined with Salvia miltiorrhiza injection, 43 cases) and insulin group (insulin alone treated group, 43 cases). After treatment, the clinical efficacy and symptom improvement (abdominal pain disappear time, abdominal tenderness relief time, gastrointestinal function recovery time). Counting data were compared using χ2 test, t test was used to compare measurement data, P <0.05 means the difference was statistically significant. Results After treatment, the total effective rate in the combined group was 97.7% higher than that in the insulin group (81.4%), with significant difference (P <0.05). (3.87 ± 0.18) days in abdominal pain, 4.94 ± 1.34 days in abdominal tenderness and 3.98 ± 0.21 days in gastrointestinal function recovery group were significantly lower than those in insulin group (8.54 ± 1.47 and 8.79 ± 2.20), (6.75 ± 1.33) d, respectively. There was significant difference between the two groups (all P <0.05). Conclusion The clinical efficacy of insulin plus salvia miltiorrhiza injection in the treatment of HLP is remarkable. Abdominal pain, abdominal tenderness and gastrointestinal function recovery are ideal.