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目的:探讨高强度聚焦超声联合曼月乐治疗慢性盆腔痛的临床效果及安全性。方法:38例患者均为药物治疗无效而行手术和高强度聚焦超声联合曼月乐治疗,每组各19例;对两组患者治疗前和治疗后7天、1月、2月的VAS、血浆P物质和治疗后3、6月满意度进行评价及统计学分析。结果:两组患者于治疗后1、2月VAS及血浆P物质较治疗前显著降低(P<0.05),疼痛明显缓解或消失;手术组治疗后1、2月的VAS及血浆P物质小于高强度聚焦超声联合曼月乐组。治疗后3、6月手术组满意度呈下降趋势,差异有统计学意义(P<0.05);高强度聚焦超声联合曼月乐组的满意度保持水平基本稳定并优于手术组。结论:高强度聚焦超声联合曼月乐治疗慢性盆腔痛的疗效确切,是一种安全、有效方法。
Objective: To investigate the clinical effect and safety of high intensity focused ultrasound combined with Mirena in the treatment of chronic pelvic pain. Methods: Thirty-eight patients were ineffective and underwent surgery and high-intensity focused ultrasound combined with Mirena, with 19 patients in each group. Before treatment, 7 days after treatment, 1 month and 2 months after treatment, VAS, Plasma substance P and 3, 6 months after treatment satisfaction evaluation and statistical analysis. Results: The levels of VAS and plasma P in the two groups after treatment were significantly lower than those before treatment (P <0.05), and pain was relieved or disappeared. VAS and plasma P in the two groups were less than high Intensity focused ultrasound combined with the Mirena group. After 3 and 6 months of treatment, the satisfaction of surgery group showed a downward trend, the difference was statistically significant (P <0.05); high intensity focused ultrasound combined with Mirena group satisfaction remained stable and better than surgery group. Conclusion: High intensity focused ultrasound combined with Mirena is effective in treating chronic pelvic pain and is a safe and effective method.