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目的:观察致康胶囊对混合痔高频电容场痔疮治疗术(HCPT)术后预防出血,加快创面愈合的临床疗效。方法:284例混合痔HCPT术后患者随机分为治疗组149例和对照组135例。治疗组用致康胶囊0.6 g,去胶囊壳后取药粉直接肛缘创面上药,qd,同时用致康胶囊2.4 g溶于温水500 ml坐浴,qn;对照组用碘伏棉球消毒后凡士林纱布覆盖创面,qd,同时采用高锰酸钾0.1 g溶于温水500 ml坐浴,qn。观察两组术后第1,3,7天创面出血量及分泌物量记录两组创面愈合时间及药品不良反应。结果:术后第1,3,7天,治疗组术后创面出血评分及术后创面分泌物评分均优于对照组(P<0.05或0.01),创面愈合时间明显短于对照组(P<0.01)。结论:致康胶囊可促进HCPT术后创面修复,减少术后创面出血,安全性好。
Objective: To observe the clinical effect of Zhikang Capsule in preventing hemorrhage and accelerating the healing of wound after mixed hemorrhoid high frequency capacitance field hemorrhoids treatment (HCPT). Methods: 284 patients with mixed hemorrhoids HCPT were randomly divided into treatment group (149 cases) and control group (135 cases). The treatment group with Zhikang capsule 0.6 g, after taking the capsule shell to take medicine directly on the anal wound, qd, at the same time with zhikang capsule 2.4 g dissolved in warm water 500 ml bath, qn; control group with iodophor tampon disinfection Vaseline gauze to cover the wound, qd, while using potassium permanganate 0.1 g dissolved in warm water 500 ml bath, qn. The wound hemorrhage and secretions on the 1st, 3rd, 7th day after operation were observed. The wound healing time and adverse drug reactions were recorded. Results: On the 1st, 3rd, 7th day after operation, the wound hemorrhage score and postoperative wound secretion score of the treatment group were better than those of the control group (P <0.05 or 0.01), and the wound healing time was significantly shorter than that of the control group (P < 0.01). Conclusion: Zhikang capsule can promote wound healing after HCPT and reduce wound bleeding after operation, which is safe.