四环素族抗生素(以下简称“四族”)是临床上常用的一类抗生素。本文就影响“四族”吸收的因素.配伍应用效果和毒副作用等与同道共相研讨。影响“四族”吸收的某些因素“四族”能与多种多价金属离子形成络合物。“四族”与含二价和三价金属离子(Fe++、Al~(+++)、Ca~(++)、Mg~(++)、Bi~(+++)等)的药物合用,可 Tetracycline antibiotics (hereinafter referred to as “Si family”) is a commonly used clinical class of antibiotics. This article discusses the factors that affect the absorption of the “four tribes”, the effects of compatibility and the toxic and side effects. Some Factors Affecting the Absorption of “Four Kinds of Clans” The “Four Kinds of Nationalities” can form complexes with many polyvalent metal ions. The “four families” are combined with drugs containing divalent and trivalent metal ions (Fe ++, Al ~ (+++), Ca ~ (++), Mg ~ (++), Bi ~ (+++), etc.) ,can