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研究了中药中空液体栓剂的制备。体外溶出试验表明中空液体栓剂具有明显的速释效果。兔体内生物利用度参数证明中空栓的Ｔｍａｘ、Ｃｍａｘ和ＡＵＣ均优于普通栓剂、肌肉注射和口服给药。
The preparation of hollow liquid suppository was studied. In vitro dissolution tests showed that hollow liquid suppositories have a significant immediate release effect. Bioavailability parameters in rabbits demonstrated that Tmax, Cmax and AUC of the hollow suppository were better than those of ordinary suppository, intramuscular injection and oral administration.