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为探索吡喹酮对华枝睾吸虫病的治疗效果,我们于1979年5～6月对自然感染华枝睾吸虫的病猫,用吡喹酮进行口服给药治疗,初步实验结果显示吡喹酮对猫华枝睾吸虫有肯定杀虫效果。现将研究方法及结果报告如下: 研究方法实验动物为自然感染华枝睾吸虫的家猫(均经粪检虫卵证实)体重1.40～3.15公斤。药物来源及配制: 用药为吡喹酮,由中国医学科学院寄生虫病研究所提供(1978);参照该所治疗日本血吸虫的药物配制方法,将吡喹酮混悬于0.1％十二烷基磺酸钠和1％西黄耆胶中,每毫升混悬液含吡喹酮40毫克。实验分组:
To explore the effect of praziquantel on the treatment of Clonorchiasis sinensis, we administered praziquantel orally to sick cats naturally infected with Clonorchis sinensis from May to June 1979. The preliminary experimental results showed that praziquantel Ketoridinolyticosterone has a positive insecticidal effect. Now the research methods and results are reported as follows: Study methods Experimental animals are natural cats infected with Clonorchis sinensis (confirmed by fecal insects eggs) weight 1.40 ~ 3.15 kg. Drug source and preparation: The drug is praziquantel, provided by the Institute of Parasitic Diseases, Chinese Academy of Medical Sciences (1978); praziquantel is suspended in 0.1% dodecyl sulphate with reference to the drug formulation of the treated Schistosoma japonicum Sodium sulfate and 1% tragacanth, the per suspension containing praziquantel 40 mg. Experimental grouping: