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目的:对数种心血管疾病患者进行血锂质量浓度测定,探讨其与心血管疾病之间的关系。方法:选不同种类心血管疾病患者110例及31例正常人作为对照,抽取外周静脉血,测定血浆锂与红细胞内锂的含量,并进行统计学分析。结果:各类心血管疾病患者红细胞内锂的含量低于对照组(P<0.01);随着心功能不全的逐渐加重,血浆锂含量亦逐渐降低。结论:提高血浆或红细胞内微量元素锂的含量,可望降低心血管疾病的发病率并改善心脏功能。
OBJECTIVE: To determine the blood lithium concentration in several kinds of cardiovascular diseases and explore its relationship with cardiovascular diseases. Methods: 110 patients with different types of cardiovascular diseases and 31 healthy controls were selected as the control. Peripheral venous blood was drawn and the contents of lithium in plasma and erythrocytes were measured and analyzed statistically. Results: The content of lithium in erythrocytes in patients with various cardiovascular diseases was lower than that in the control group (P <0.01). With the gradual increase of cardiac insufficiency, the plasma lithium content also decreased gradually. Conclusion: Increasing the content of trace element lithium in plasma or erythrocytes is expected to reduce the incidence of cardiovascular diseases and improve cardiac function.