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目的 :探索A型肉毒毒素 (BT—A)治疗偏侧面肌痉挛 (HFS)的合适剂量及合适部位。方法 :对 86例HFS病人按不同剂量及不同部位分别注射BT—A ,共 2 36例次 ,随访 1～ 2 8个月观察其疗效情况。结果 :①不同剂量疗效比较差异无显著性 ,副作用比较差异有显著性。② 4点与 6点注射疗效比较差异有显著性 ,副作用比较差异无显著性。结论 :局部注射BT—A治疗HFS是一种安全有效简便易行的治疗手段 ,以小剂量、多部位为宜。
Objective: To explore the suitable dose and suitable site of botulinum toxin type A (BT-A) for the treatment of hemifacial spasm (HFS). Methods: Totally 86 cases of HFS were injected with BT-A at different doses and different sites for a total of 2 36 cases. The follow-up period of 1 to 28 months was used to observe the curative effect. Results: ① There was no significant difference in the efficacy of different doses of side effects were significant differences. ② 4:00 and 6:00 injection compared the difference was significant, no significant difference in side effects. Conclusion: Local injection of BT-A in treatment of HFS is a safe, effective, simple and easy treatment. It is advisable to use small doses and multiple sites.