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本文主要目的是测量头颈部放疗者的涎液表皮生长因子(epidermal growth factor,EGF)水平,并评价EGF与放疗性口腔粘膜炎严重程度是否相关。 材料和方法 将13例头颈部放疗患者和18例与之性别、年龄相当的健康人进行配对研究。在放疗前、中、后分别收集全涎液,测定涎液全蛋白(totalprotein,TP)和EGF浓度,并记录口腔粘膜炎严重程度。 结果和讨论 放疗前涎液EGF和标准化EGF水平及TP水平在放疗组和健康组间的差异不明显。
The main purpose of this article is to measure the epidermal growth factor (EGF) levels of sputum in head and neck radiotherapy patients and to evaluate whether EGF is related to the severity of radiotherapy oral mucositis. Materials and Methods Paired studies were performed on 13 patients with head and neck radiotherapy and 18 healthy individuals with similar age and gender. All sputum was collected before, during and after radiotherapy. Total protein (TP) and EGF concentrations were measured and the severity of oral mucositis was recorded. Results and Discussion There was no significant difference in sputum EGF and standardized EGF levels and TP levels between radiotherapy and healthy groups before radiotherapy.