论文部分内容阅读
目的临床分析对肺结核患者使用抗结核药物所致的肝功能损害情况。方法选取2016年4月至2017年4月在我院就诊的136例肺结核患者,均采用抗结核药物治疗,统计肝功能损害的发生率,观察肝功能表现、损害程度,并分析年龄、疗次等因素与其发生的关联性。结果年龄≥60岁的肺结核患者,其肝功能损害的发生率要显著高于<60岁的肺结核患者,明显可见统计学意义(P<0.05);肺结核复治者的肝功能损害发生率显著高于初治者,可见统计学意义(P<0.05)。结论在临床应用抗结核药物治疗肺结核患者时,需密切关注病情变化,督促患者及时复查肝功能,以早发现肝功能损害,早干预治疗,从而提高肺结核的治疗效果,并最大限度的改善患者预后生活质量。
Objective To analyze the clinical damage of liver function induced by anti-tuberculosis drugs in patients with pulmonary tuberculosis. Methods A total of 136 patients with tuberculosis who were treated in our hospital from April 2016 to April 2017 were enrolled in this study. All patients were treated with anti-TB drugs. The incidence of hepatic dysfunction was calculated. The liver function was observed and the degree of damage was observed. And other factors associated with their occurrence. Results The incidence of liver dysfunction in patients with pulmonary tuberculosis≥60 years old was significantly higher than that in patients <60 years old with obvious statistical significance (P <0.05). The incidence of liver dysfunction in patients with pulmonary tuberculosis was significantly higher In the first rule, we can see the statistical significance (P <0.05). Conclusion In the clinical application of anti-tuberculosis drugs in patients with pulmonary tuberculosis, we should pay close attention to changes in the condition, urge patients to promptly review the liver function, early detection of liver damage, early intervention, thereby enhancing the therapeutic effect of tuberculosis and maximize the prognosis of patients Quality of Life.