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本文应用HRP与免疫组化结合的方法研究加压素神经元在下丘脑的分布及其与垂体后叶的关系,结果表明:下丘脑视上核、室旁核、视上核后部、视交叉上核、前连合核、终纹床核、环形核、穹窿核、视前区、下丘脑内、外侧区、室周灰质、室管膜层及下丘脑一些血管周围均有加压素神经元分布。室管膜层、视上核的软膜面及一些大血管周围有丰富的神经元突起,有些甚至接触到脑脊液或游离到血管腔中。除视交叉上核外,上述其余核区均有发纤维投射到垂体后叶。本文结果提示:加压素可能通过三种途经释放:①释放到垂体后叶;②直接释放到脑脊液;③直接释放到下丘脑的血管腔内。
In this paper, HRP and immunohistochemistry combined with the method of vasopressin neurons in the hypothalamus distribution and its relationship with the posterior pituitary, the results show that: hypothalamic supraoptic, paraventricular nucleus, supraoptic nucleus, optic chiasm Upper nucleus, anterior commissure nucleus, striation nucleus, annular nucleus, vault nucleus, preoptic area, hypothalamic area, lateral area, periventricular gray matter, ependymal layer and hypothalamic vessels around the vasopressin neurons Yuan distribution. The ependymal layer, supracapeal soft membrane surface and some large blood vessels around the rich neuronal processes, and some even contact with cerebrospinal fluid or free to the vessel lumen. Except optic suprachiasmatic nucleus, the above remaining nuclear region have hair fiber projection to the posterior pituitary. The results suggest that: vasopressin may be released through three ways: ① release to the posterior pituitary; ② direct release to the cerebrospinal fluid; ③ direct release to the hypothalamic vascular cavity.