论文部分内容阅读
水扬酸偶氮磺胺吡啶(SASP)已广泛用于治疗溃疡性结肠炎,但该药较贵且副作用较大。而5-氨基水扬酸(5-ASA)虽无副作用但亦很贵,且药源供应困难。1989年我们根据国外介绍,使用4-氨基水扬酸(4-ASA,PAS)保留灌肠治疗溃疡性结肠炎12例取得较满意疗效,现报道如下。临床资料本组病例诊断按1978年全国消化系病学术会议所拟定的诊断标准。病变范围以左半结肠为主。12例中男性7例,女性5例,年龄27～56岁,病程3月～4年。初发型活动期9例,其中轻度者5例,中度者4例;慢性复发型活动期3例,其中轻度者2例,中度者1例。
Sulphasalazine (SASP) has been widely used in the treatment of ulcerative colitis, but the drug is more expensive with a large side effect. However, 5-aminosalicylic acid (5-ASA) has no side effects but is also expensive, and drug supply is difficult. In 1989, according to the introduction of foreign countries, 4-aminosalicylic acid (4-ASA, PAS) retention enema in 12 cases of ulcerative colitis obtained more satisfactory curative effect, are reported below. Clinical data The diagnosis of this group of patients according to the 1978 National Digestive Disease Conference prepared by the diagnostic criteria. The main lesion to the left colon. 12 cases of male 7 cases, 5 females, aged 27 to 56 years, duration of 3 months to 4 years. Initial activity in 9 cases, of which mild in 5 cases, moderate in 4 cases; chronic recurrent activity in 3 cases, of which mild in 2 cases, moderate in 1 case.